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School of Life Science
Position: Home>>Faculty>>School of Life Science >>Content


YIN Jiangxia     WANG Juan     WANG Xiangyu     LU Ziyin    
LI Chengcheng     HE Jianwei     HE Yin     ZHANG Li    
ZENG Yingyue     YANG Zhe     JIANG Yiting     DENG Xin    
ZHENG Fangliang     WANG Hongyan     TANG Yi     RUAN Yanan    
LIU Jianli     SUN Jun     LI Donglai     HUI Jing    
HE Jianwei     BEN Songbin     AI Haixin     WEI Jie    
ZHU chunyu     BI Xiuli     CAO xiangyu     LU Xiuli    
JIN Lili     CAI Tiange     HAN Yang     WANG Qiuyu    
LIU Hongsheng     WAN Dongmei    

LIU Jianli
2016-12-05 14:13  

LIU Jianli, Associate professor of School of Life Science, Liaoning University, He completed his PhD in Genetics from China Medical University in 2011, received B.S. degrees in Biological Techniques in 2002 and M.S. in Biochemistry and Molecular Biology in 2005 from Shenyang Agricultural University respectively. As a visiting Scholar, He visited Departments of Environmental Medicine, NYU from Sep,2014 to Aug,2015.

Research Interests:

Our lab research focuses on environmental medicine and disease, Nutrition and epigenetic involved in cellular function, nutritional prevention involved in cellular signaling and Molecular mechanism of chronic disease.

Main grant: 

1. The interaction between polysaccharide extracted from Lentinus edodes mycelium and lactoferrin and the protective effects of LMP-LF complex on islet β cell damage induced by high glucose, National Nature Science Foundation of China (NSFCNo. 3191101726), 2020.04-2022.03

2. Pulmonary diseases induced by PM2.5 based on inflammatory response and signal transduction pathway, Liaoning Provincial Doctoral Research Startup Project (No.20170520258), 2017-2019

3. Inhibition of PM2.5-induced bronchial epithelial cell injury based on NF-κB and NLRP3 inflammatory signaling pathway by anthocyanins, Liaoning Provincial Department of Education Science and Technology Research Project (No. LQN201714), 2017-2019

4. Plant polyphenols inhibit cell damage induced by PM2.5 and its main components and the underlying mechanism, Shenyang city Middle-aged Technological Innovation Talent Support Plan Project (No. RC180240), 2018 -2019

Publications (last 5 years):

1. Xiangyu Cao, Siqi Tian, Mingyang Fu, Yanmei Li, Yueling Sun, Jianli Liu*, Yue Liu. Resveratrol protects human bronchial epithelial cells against nickelinduced toxicity via suppressing p38 MAPK, NF-κB signaling, and NLRP3 inflammasome activation [J]. Environmental Toxicology. 2020, 1-10. (IF 2.646)

2. Jianli Liu, Zhijun Yang, Ye Cheng, Qiong Wu, Yin He, Qijiu Li. Xiangyu Cao. Eriodictyol and naringenin inhibit the formation of AGEs: An in vitro and molecular interaction study [J]. Journal of Molecular Recognition, 2020, 33(1): 1-7. (IF 1.919)

3. Jianli Liu, Siqi Tian, Mingyang Fu, Yin He, Hui Yu, Xiangyu Cao, Yiyang Cao, Hanyuan Xu. Protective effects of anthocyanins from Coreopsis tinctoria against oxidative stress induced by hydrogen peroxide in MIN6 cells. Chemistry & Biodiversity, 2020, 17, e1900587: 1-13. (IF 1.449)

4Xiangyu Cao, Yonglin He, Yuchi Kong, Xueying Mei, Yapeng Huo, Yin He, Jianli Liu. Elucidating the interaction mechanism of eriocitrin with β-casein by multi-spectroscopic and molecular simulation methods [J]. Food Hydrocolloids, 2019, 94(9): 63-70. (IF 5.839)

5. Xiangyu Cao, Shuai Wang, Ruochen Bi, Siqi Tian, Yapeng Huo, Jianli Liu* Toxic effects of Cr(VI) on the bovine hemoglobin and human vascular endothelial cells: Molecular interaction and cell damage [J]. Chemosphere, 2019, 222 (1): 355-363. (IF 5.108)

6. Xiangyu Cao, Dan Liu, Ruochen Bi, Yonglin He, Yin He, Jianli Liu. The protective effects of a novel polysaccharide from Lentinus edodes mycelia on islet β (INS-1) cells damaged by glucose and its transportation mechanism with human serum albumin [J]. International Journal of Biological Macromolecules, 2019, 134(8): 344-353. (IF 4.784)

7Jianli Liu, Yuchi Kong, Jingyi Miao, Xueying Mei, Shuyao Wu, Yichen Yan, Xiangyu Cao. Spectroscopy and molecular docking analysis reveal structural specificity of flavonoids in the inhibition of α-glucosidase activity. International Journal of Biological Macromolecules, 2019, doi: 10.1016/j.ijbiomac.2019.10.184. (IF 4.784)

8. Xiangyu Cao, Dan Liu, Ying Xia, Tiange Cai, Yin He, Jianli Liu*. A novel polysaccharide from Lentinus edodes mycelia protects MIN6 cells against high glucose-induced damage by MAPK and Nrf2 pathways [J]. Food & Nutrition Research, 2019, 63(6): 1598-1606. (IF 2.553)  

9. Jianli Liu, Yonglin He, Shuai Wang, Yin He, Weiyu Wang, Qijiu Li, Xiangyu Cao*. Ferulic acid inhibits advanced glycation end products (AGEs) formation and mitigates the AGEs-induced inflammatory response in HUVEC cells [J]. Journal of Functional Foods, 2018, 48: 19-26. (IF 3.47)

10. Xiangyu Cao, Shuai Wang, Siqi Tian, Hong Lou, Yuchi Kong, Zhijun Yang, Jianli Liu. Spectroscopic and molecular modeling studies on the interactions of fluoranthene with bovine hemoglobin [J]. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2018, 203(5): 301-307. (IF 2.931)

11. Jianli Liu, Shuai Wang, Siqi Tian, Yin He, Hong Lou, Zhijun Yang, Yuchi Kong, Xiangyu Cao. Nobiletin inhibits breast cancer via p38 mitogen-activated protein kinase, nuclear transcription factor-κB, and nuclear factor erythroid 2-related factor 2 pathways in MCF-7 cells [J]. Food & Nutrition Research, 2018, 62: 1323-1332. (IF 2.553)  

12. Jianli Liu, Yonglin He, Dan Liu, Yin He, Zhipeng Tang, Hong Lou, Yapeng Huo, Xiangyu Cao. Characterizing the binding interaction of astilbin with bovine serum albumin: a spectroscopic study in combination with molecular docking technology [J]. RSC Advances, 2018, 8: 7280-7286. (IF 3.049)

13. Xiangyu Cao, Yonglin He, Dan Liu, Yin He, Xiao Hou, Ye Cheng, Jianli Liu*. Characterization of interaction between scoparone and bovine serum albumin: spectroscopic and molecular docking methods [J]. RSC Advances, 2018, 8: 25519-25525. (IF 3.049)

14. Jianli Liu, Meijia Liu, Shuai Wang, Yin He, Yapeng Huo, Zhijun Yang, Xiangyu Cao. Alantolactone induces apoptosis and suppresses migration in MCF7 human breast cancer cells via the p38MAPK, NF-κB and Nrf2 signaling pathways [J]. International Journal of Molecular Medicine, 2018, 42(7): 1847-1856. (IF 2.928)

15. Yin He, Xiangyu Cao, Yuchi Kong, Shuai Wang, Ying Xia, Ruochen Bi, Jianli Liu*. Apoptosis-promoting and migration-suppressing effect of alantolactone on gastric cancer cell lines BGC-823 and SGC-7901 via regulating p38MAPK and NF-κB pathways [J]. Human and Experimental Toxicology, 2019, 38(10): 1132-1144. (IF 2.171)

16. Xiangyu Cao, Ying Xia, Meng Zeng, Weiyu Wang, Yin He, Jianli Liu*. Caffeic acid inhibits the formation of advanced glycation end products (AGEs) and mitigates the AGEs-induced oxidative stress and inflammation reaction in human umbilical vein endothelial cells (HUVECs) [J]. Chemistry & Biodiversity, 2019, 16(10): 1-9. (IF 1.449)

17. Jianli Liu, Zhijun Yang, Yuchi Kong, Yin He, Yongliang Xu, Xiangyu Cao. Antitumor activity of alantolactone in lung cancer cell lines NCI-H1299 and Anip973 [J]. Journal of Food Biochemistry, 2019, 43(5): 1-10. (IF 1.358)

18. Jianli Liu, Yuchi Kong, Jingyi Miao, Yonglin He, Ruochen Bi, Yin He, Xiangyu Cao. Analysis of the binding mechanism between ophenylenediamine and bovine hemoglobin by molecular spectroscopy and molecular modeling methods [J]. Spectroscopy Letters, 2019, 52(10): 622-632. (IF 1.081)

19. Xiangyu Cao, Zhijun Yang, Yonglin He, Ying Xia, Yin He, Jianli Liu*. Multispectroscopic exploration and molecular docking analysis on interaction of eriocitrin with bovine serum albumin [J]. Journal of Molecular Recognition, 2019, 2779(1): 1-8. (IF 1.868)

20. Xiangyu Cao, Jianli Liu*, Wei Yang, Xiao Hou, Qijiu Li. Antitumor activity of polysaccharide extracted from Pleurotus ostreatus mycelia against gastric cancer in vitro and in vivo [J]. Molecular Medicine Reports, 2015, 12(2): 2383–2389. (IF 1.868)

 Contact Info:

Address: 66 Chongshan Road, Huanggu District, Shenyang 1100036

Phone: (86)24-62202232

Email: liujianli@lnu.edu.cn


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