Name: LI Li

Contact: School of Pharmaceutical Science, Liaoning University, No. 66, Chongshan Road Shenyang, Liaoning Province, P.R.China, 110036

Telephone：86-24-62202469 (O)

E-Mail：lily63k@163.com

EDUCATION

Jul. 2007- Jul. 2010

Doctor degree (Pharmaceutics, Shenyang Pharmaceutical University) 

Thesis title: Design and evaluation of the transdermal patches for site-specific delivery of

Letrozole

Sep. 2002 - July. 2005 

Master degree (Pharmaceutics, Shenyang Pharmaceutical University) 

Thesis title: The research of SEDDS soft capsules of vitamin E nicotinate

Sep. 1996 - July. 2000

Bachelor degree (Pharmaceutics, Shenyang Pharmaceutical University) 

Thesis title: The research of calcium alginate gel beads: Sustained release preparation

PROFESSIONAL EXPERIENCE

TEACHING

Jan. 2015- Present

Associate professor   School of Pharmaceutical Science, Liaoning University

Jul. 2007- Dec. 2014

Lecturer   School of Pharmaceutical Science, Liaoning University

Jul. 2005- Jul. 2007

Tutor   School of Pharmaceutical Science, Liaoning University

WORKING

Jul. 2000- Aug. 2002

Technician Harbin Pharmaceutical Group pharmaceutical Sixth Factory

RESEARCH

Host major projects:  

1. Construction of new oral carriers: Metals-Metal Organic Frameworks (MOFs).

Natural Science Foundation of Liaoning province, 20180510016, 2019-MS-153 

2. Construction and transport mechanism of Nanosuspension-based gel of ketoprofen for

       transdermal delivery.

Foundation of Educational Committee of Liaoning province, No. L2014006

3. Preparation of microemulsion gel of volatile oil from C. nudiflora and its antimicrobial

       Activity

Youth Foundation of Liaoning University, No. 2010LDQN20

Participation other projects:  

1. Percutaneous absorption of reversibility and its mechanism of l-carveol ester derivative

National Natural Science Foundation of China, No. 30973654 

2. Mechanism oxidative stress in pancreatic β cells and regulation of insulin gene expression of mushroom mycelium polysaccharide based anti-MAPK pathway

National Natural Science Foundation of China, No.31240005

1. Study on bexarotene nanocrystalline: treatment of lung cancer targeted drugs

Science and Technology Project of Liaoning Province, No. 2013030038-301

2. Research and development of gambogic acid lipid microspheres

  Human Resources and Social Security Department Project of Liaoning Province

3. Research of butyric acid clevidipine nanoemulsion injection

Foundation of Educational Committee of Liaoning province, No. L2013011

4. Study of panax notoginseng saponins osmotic pump tablets

  Foundation of Educational Committee of Liaoning province, No. L20060357

5. Detection technology services of variety antibiotics in animal feed

  Science and Technology Project of Shenyang, No. F1-1-255-00

6. Preparation and microbial transformation of total paeony glucosides osmotic pump tablets

  Science and Technology Project of Shenyang, No. F10-205-1-28

7. Biological function and its possible mechanism of Millet Peptides  

Foundation of Educational Committee of Liaoning province，No. L20100154

Patent:

1. A method of nanosuspension-based gel of ketoprofen for transdermal delivery

Patent number CN 104337757 A    Independent winner.

2. A method of the transdermal patches for site-specific delivery of letrozole

Patent number ZL 200910248727.0   The participants in the second.

3. A method of total paeony glucosides SMEDDS soft capsule

Patent number ZL 201110293594.6   The participants in the fourth.

REFEREED JOURNAL ARTICLES

Aticle

1. Li Li, Chunjiao Pan，Zhongqiu Guo, Bingmi Liu, Hao Pan, Haotian Wu, Yu Liu Y*. Exploration on the adsorption mechanism of aminopyrimidines and quinazoline compounds on graphene oxide: Hydrophobicity and structure-controlled release process. Materials Express, 2019, 9(5): 419-428.

2. Li Li, Yu Liu, Jinjing Wang, Lijiang Chen*, Wenjun Zhang,Xichen Yan. Preparation, in vitro and in vivo evaluation of bexarotene nanocrystals with surface modification by folate-chitosan conjugates. Drug Deliv, 2016, 23(1): 79-87.

3. Li Li, Yu Liu, Lijiang Chen*, Jinghong Rrong, Yi Li, Fang Wang, En Lu. Nanosuspension-based gel of ketoprofen for transdermal delivery: preparation, in vitro and in vivo penetration evaluation, Latin American Journal of Pharmacy, 2016, 35(5):980-90.

4. Li Li, Yu Liu, Xin Wan, Yang Liu, Jinjing Wang, Lijiang Chen*, Studies on Pharmacokinetics and Tissue Distribution of Bexarotene Nanocrystals with Surface Modification by Folate-Chitosan Conjugates, Latin American Journal of Pharmacy, 2015, 34(4):712-718.

5. Li Li, Jijun Liang, Yu Liu, Lijiang Chen*, Wenjun Zhang, En Lu, Simultaneous determination of luteolin and ayanin in rat plasma by HPLC-MS-MS and its application in a pharmacokinetic study, Latin American Journal of Pharmacy, 2014, 33(9):1475-1480.

6. Li Li, Xiaoyang Yang, Yu Liu*, Lijiang Chen*, Xin Jin, Studies on pharmacokinetics and tissue distribution of curcumol Liposome, Latin American Journal of Pharmacy, 2014, 33(5):709-716.

7. Li Li, Xinlan Xu, Yu Liu, Yinghua Sun, Manli Wang, Nanxi Zhao, Liang Fang*, Transdermal delivery of letrozole: effects of vehicles and organic acids on its permeation through rat skin, Journal of Chinese Pharmaceutical Sciences, 2011, 20(1):57-62.

8. Li Li, Liang Fang*, Xinlan Xu, Yu Liu, Yinghua Sun, Zhonggui He, Formulation and biopharmaceutical evaluation of a transdermal patch containing letrozole, Biopharm. Drug Dispos, 2010, 31:138-149.

9. Li Li, Xinlan Xu, Liang Fang*, Yu Liu,Yinghua Sun, Mangli Wang, Nanxi Zhao, Zhonggui He, The transdermal patches for site-specific delivery of letrozole: A new option for breast cancer therapy, AAPS PharmSciTech, 2010, 11(3):1054-1057. 

Publication

《Pharmaceutics》Shanghai Scientific & Technical Publishers, editor, 2011.

  ACHIEVEMENT AND AWARDS

Academic achievement:

1. Gain Natural science academic achievement in Liaoning in 2011. Third prize. Independent winner.

2. Gain Natural science academic achievement in Shenyang in 2012. Second prize. Independent winner.

3. Gain Natural science academic achievement in Liaoning in 2010. First prize. The participants in the second.

4. Gain Natural science academic achievement in Shenyang in 2014. Third prize. The participants in the second.

Teaching awards:

1. The first prize of seventh Liaoning university young teacher’s competition in 2013.

2. The beautiful women in Liaoning University in 2014.

3. The “outstanding player” award in the Shenyang "Millions of skilled personnel training projects" competition in 2013.

4. The “experimental teaching and administration” award in Liaoning University in 2014.

  COURSES TAUGHT

Pharmaceutics

Pharmaceutical Engineering

Pharmacoeconomics